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KMID : 1189420100230010001
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2010 Volume.23 No. 1 p.1 ~ p.7
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Effects of Kami-bangpungtongseong-san Extracts on the Mouse Skin Toxicated by Mercury
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Abstract
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Objective : Mercuric chloride is excreted in the urine and stool. Bangpungtongseong-san(BT) has been used commonly skin disease and has diuresis and excretion effect. This study is aimed to find out effects of Kami- bangpungtongseong-san(KBT) on the skin disease toxicated by mercury. Method : Experiment was conducted with No treated group(Normal group), Mercuric chloride subcutaneous injection group(Control group) and Kami-bangpungtongseong-san-treated group (Sample group). KBT Extracts were delivered orally in 7 days in sample group. We observed epithelial cell hyperplastic, angiogenesis, inflammatory cell infiltration of skin. For the charting the results, image analysis was taken. The result of image analysis was verified significance by Sigmaplot 2000(P<0.05). Result : This study shows an relieving epithelial cell hyperplastic, angiogenesis, inflammatory cell infiltration of exposure skin on mercuric chloride. Conclusion : According to the result of study, we can expect to the effect of KBT extracts’ therapeutic action to tissue injuries of the mice’ skin on acute mercurial toxication.
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KEYWORD
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Kamibangpungtongseong-san Extracts, Acute mercurial toxication, Skin, Mercuric chloride
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